临床医生报告结局（Clinician-Reported Outcome, ClinRO）
临床医生报告结局（Clinician-Reported Outcome, ClinRO）：A type of clinical outcome assessment. A measurement based on a report that comes from a trained health-care professional after observation of a patient’s health condition. 1)
Most ClinRO measures involve a clinical judgment or interpretation of the observable signs, behaviors, or other manifestations related to a disease or condition. ClinRO measures cannot directly assess symptoms that are known only to the patient.
ClinRO measures include:
Reports of particular clinical findings (e.g., presence of a skin lesion or swollen lymph nodes) or clinical events (stroke, heart attack, death, hospitalization for a particular cause), which can be based on clinical observations together with biomarker data, such as electrocardiogram (ECG) and creatine phosphokinase (CPK) results supporting a myocardial infarction
Rating scales, such as:
- Psoriasis Area and Severity Index (PASI) for measurement of severity and extent of a patient’s psoriasis
- Hamilton Depression Rating Scale (HAM-D) for assessment of depression